MEDICAL CONCEPT -UNPUBLISHED--3

NEW TREATMENT FOR FITS.
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One of the commonest cause of neonatal fits, is intracranial hemorrhage,&C.T. scan pictures

have been published in Nelson's text book even 40 years back.We now understand that

intracranial hemorrhage can occur antenatal ,perinatal,&post Natal,leading to fits.THERE

ARE FEW CHILDREN BELOW ONE YEAR OF AGE WHO GET UNCONTROLLED CONVULSIONS,BY CONVENTIONAL

ANTICONVULSANTS, IN SPITE OF DETAILED RELEVANT INVESTIGATIONS,WHICH DO NOT COVER ROUTINE BLOOD

COAGULATION PROFILE.Recently this Auther has come across3 children ,below one year , in the

last one year's hospital service,with seizure disorders uncontrolled by three

anticonvulsants(eptoin,phenobarb,sodium valproate)These children had higher values of
prothrombin time/INR,indicating lessened coagulation,&tendency for minute microscopic capillary

bleeds inside the brain.The convulsions have stopped after addition of

ETHAMSILATE(hemostat)&injection of VITAMIN K ,WITHIN 3 MONTHS Though it requires ,a large,systamatic&scientific analyticalstudy in a childrens hospital like ICH MADRAS,
to confirm &conclude it defifinitele indicates that there is a place for including prothrombin

time&inr in the neonatal screeninig procedure&perhaps to all uncontrolled seizure disorders
under 3 anticonvulsant drugs,in the under one year age group children.